In this video, Prof Fendler discusses the indications for a PSMA-PET/CT scan in prostate cancer, the initial preparation required by staff including patient education, consent, hydration and the use of furosemide to reduce bladder uptake. He also covers the types of radiotracers, the administration protocols, and the importance of accurate interpretation of PSMA-PET/CT scan images to avoid false positives. Additionally, he highlights the need for proper imaging techniques and the potential pitfalls in interpreting PSMA-PET/CT scans.